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Importantly, all GLP-1 receptor agonists carry a boxed warning about the risk of thyroid C-cell tumors and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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Retrospective studies, detailed below, suggest that GLP-1s appear to both prevent addictions from occurring in patients taking them for diabetes or obesity, and to prevent relapse in patients with a history of substance use disorders

The reconstituted solution belongs in the refrigerator, not the freezer

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