the exact amount depends on the concentration you want
FTPP vs semaglutide and tirzepatide GLP-1 receptor agonists like semaglutide and dual agonists like tirzepatide and retatrutide represent the current gold standard in pharmaceutical weight loss
With growing evidence on synergy, it's a promising tool for healthspan extension
Chronic Dosing Protocol: AOD9604 administered intraperitoneally at 250 g/kg/day hGH administered at 1 mg/kg/day Treatment duration: 1428 days depending on cohort Daily administration via intraperitoneal injection Acute Testing Protocol: Single AOD9604 dose: 2 mg/kg 3-AR agonist BRL37344: 250 g/kg (for comparison) Indirect calorimetry measurements performed Measured Outcomes: Body weight, food intake, white adipose tissue (WAT) and brown adipose tissue (BAT) weights, plasma glycerol levels (indicating lipolysis), and 3-AR mRNA expression in adipose tissue
These cardiovascular effects suggest potential applications in ischemic heart disease, peripheral vascular disease, and vascular injury, though clinical translation requires confirmation of effects in human subjects
