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Clinical trials, such as SYDNEY-2 and NATHAN 1, found that taking 600 to 1,200 mg daily improved nerve blood flow and reduced symptoms of neuropathy over several months or years (Ziegler et al., 2006

However, there have been reports of this dose producing side effects in healthy people [22]

Building a routine around your injections The simplest way to prevent storage mistakes is to build your injection into a routine that naturally includes returning the medication to the fridge

I frequently delay the dose increase or instruct patients to temporarily modify their diet (smaller, blander meals) before pushing them to the next tier