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Zhang T et al

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Pombo and colleagues showed that the maximal GH response to GHRP-6 requires endogenous hypothalamic GHRH (Pombo et al., 1998)

GHK-Cu has been characterized as producing broad effects on gene expression in dermal fibroblast models, with shifts observed across pathways including extracellular matrix remodeling, cellular proliferation, antioxidant response, and copper homeostasis

The most dramatic difference is observed when measuring protein levels between stage 1 and stage 3 konzo, where the most significant differences are observed with the lower limit of the 95% CI for unaffected siblings being 1.78 g/ml being as compared to the upper limit of 1.36 g/ml for the 95% CI for those with stage 3 (Supplementary Fig