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Evidence on Thyroid and Pancreatic Cancer Risks Review findings suggest that while early studies sparked fears of GLP-1 RAs increasing cancer risks or exacerbating malignancy outcomes, these fears have now been largely tempered by a growing body of reassuring and even positive data

Raina R, Chauvin A, Chakraborty R et al (2020) The role of endothelin and endothelin antagonists in chronic kidney disease

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Yang Z, Zhao Y, Zhang X, Huang L, Wang K, Sun J, Chen N, Yin W, Chen S, Zhi H, et al

These changes help cells survive and grow, but the root cause of cancer remains the accumulation of genetic mutations that disrupt normal growth control. These mutations can affect multiple metabolic pathways, which explains why enzymes like NAMPT are altered