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& Flowers, T
In a recent study, administration of exendin-4, a long-acting GLP-1RA, stimulated -cell proliferation in juvenile human islets by inducing gene expressions of calcineurin/nuclear factor of activated T cells (NFAT) signaling, a proliferating factor such as NFATC1, and a cell cycle regulator such as cyclin A1 [57]
GLP-1s have neuroprotective effects and may reduce dementia risk through improved metabolic markers and cognitive function
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Aerobic exercise training alleviates renal injury by interfering with mitochondrial function in type-1 diabetic mice
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