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The FXR and TGR5 signaling pathways regulate the liver BA synthesis and intestinal BA excretion via the FXR activation of TGR5 in the enterocytes (75)

Jest zaangaowany w faz II przemian ksenobiotykw w wtrobie, podczas ktrej przeksztaca aktywowane porednie produkty metabolizmu fazy I w rozpuszczalne w wodzie substancje, uatwiajc ich wydalanie przez nerki

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Lim JM, Letchumanan V, Tan LT, Hong KW, Wong SH, Ab Mutalib NS, et al