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Furthermore, the improvements in glucose homeostasis following prebiotic treatment are dependent on GLP-1R signaling, implicating that prebiotic-induced alterations in the microbiome restore the gutbrain axis 257

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The precipitate was washed with the same weight of 10% TCA three times, and the protein-bound form of glutathione was extracted with the same weight of 10% TCA-4% 2-mercaptoethanol as described above

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The GLP-1 analog exendin-4 demonstrated upregulation of Hsp72 (Hsp70) and activation of extracellular signal-regulated kinase (ERK) pathways in pancreatic beta-cell lines under stress conditions according to study [71]