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Within months of insulins clinical introduction, investigators began experimenting with oral dosing, often administering vast quantities of crude pancreatic extracts to replicate the glucose-lowering effects observed with injection ( During the pioneering era from the 1920s through the 1950s, oral peptide delivery was pursued primarily through empirical experimentation

You have type 2 diabetes or significant insulin resistance as Mounjaro was originally developed as a diabetes medication and has shown a strong evidence base for blood sugar control alongside weight loss

A lot of GLP-1 side effects are really meal-composition problems