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The data mentioned above demonstrates that estrogen-mediated signaling is crucial in the biology of different cell types, modifying their proliferative capacity, differentiation, and survival

Different in vitro BBB cell culture models including primary and immortalized brain endothelial cell models, have been developed to facilitate the investigation of drug permeation across the BBB (199)

Biological function and classification [edit] In eukaryotes, glutathione S-transferases (GSTs) participate in the detoxification of reactive electrophilic compounds by catalysing their conjugation to glutathione

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