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It is asking which patients stay on them, what side effects show up, how outcomes differ across agents, and what "success" actually looks like outside a trial brochure

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Komajda M, McMurray JJ, Beck-Nielsen H, Gomis R, Hanefeld M, Pocock SJ, et al

We found an average 16-fold increase in the CALR GP level 1 week after completion of 4-week intermittent fasting compared with the level before 4-week intermittent fasting