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People with very high baseline A1C and long-standing diabetes Those with pre-existing diabetic retinopathy or macular edema Patients taking insulin therapy at the same time Anyone experiencing large and rapid A1C reductions over a short period People with additional vascular risks such as high blood pressure, high cholesterol, kidney disease, or sleep apnea Many patients notice blurred vision or trouble focusing on close objects when they first begin semaglutide therapy

There have been no spontaneous reports of opportunistic infections associated with saxagliptin use

The anti-inflammatory and metabolic effects of GLP-1 agonists could theoretically reduce cancer risk by lowering inflammation and improving metabolic parameters

This deficiency can lead to a variety of symptoms, including neurological problems, liver dysfunction, and hemolytic anemia

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