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Shin YH

The main triggers are well established: UV exposure, inflammation, hormonal changes, pollution-related oxidative stress, and age-related decline in skin renewal

10.1016/0048-3575(87)90068-X 21 BryantD.CumminsI.DixonD

Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

Therefore, it is not surprising that both ACE inhibitors and AT1 antagonists are effective in reducing OS on various cardiovascular diseases ( 5.1 Endothelial dysfunction Endothelial dysfunction and OS are inextricably linked in the pathophysiology of HTN, leading to vascular damage and elevated BP