The single clinical trial that was initiated was canceled
Live imaging of synaptic vesicle exo- and endocytosis For initial experiments, fluorescence was recorded using a Nikon Eclipse TE2000-U microscope (Nikon) and an Andor iXon+ back-illuminated EMCCD camera (Model no
AF488, STAR580 and JF646 fluorophores were excited using a 485 nm, 561 nm and 640 nm laser line and the emission was detected in the 500550 nm, 605625 nm and 650720 nm range, respectively, in the STED mode
Since the capsules travel through the digestive tract, the peptide comes into direct contact with the stomach and intestinal lining
While preliminary research suggests promising mechanisms of action, BPC-157 remains largely in the preclinical stage, with only a handful of small human trials published to date