In a 104-week extension (BMI 35 subgroup), mean weight loss reached -30.3% at 12 mg meaning the curve was still descending well past 80 weeks
Keeping a warm jumper or blanket accessible at all times allows for quick adjustments when cold sensitivity flares
Supportive Therapies To maximize AOD-9604s metabolic benefits, consider integrating: Structured nutrition protocols: Moderate caloric deficit (15-20% below maintenance), adequate protein intake (0.8-1.2 g/lb body weight) to preserve lean mass, strategic carbohydrate timing around training, and whole-food focused diet to support overall metabolic health
When used together, these medications can help people who struggle with both weight issues and hypothyroidism achieve better health outcomes
Additionally, NAC has been shown to boost nitric oxide production, which aids in the dilation of blood vessels and improves blood flow