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Immune and Recovery Modulation Studies: In sleep-deprived rats and limited clinical observations, DSIP exhibited mild anti-inflammatory effects (reduced IL-6, TNF-), enhanced antioxidant enzyme activity (SOD, catalase), and accelerated physiological recovery from physical/psychological stress

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Response to treatment may in turn also impact on persistence and adherence, but cause and effect are difficult to separate

These studies underscore MSC-Exos as versatile vehicles for delivering functional mitochondria, non-coding RNAs, or enzyme-activated components to counteract ferroptosis in diabetic wounds

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