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36 studies reviewed (1993-2024) Mechanism: NO system modulation, VEGF/angiogenesis, FAK-paxillin migration pathway Clinical Status: Not FDA or EMA approved

Regular sauna use promotes sweating, which helps eliminate toxins and improves blood flow to muscles, joints and skin

By stimulating the GLP-1 and GIP receptors, it improves appetite control, enhances metabolic efficiency, and boosts insulin sensitivity

(2021) 5:NS20210028

According to a study by Hays (2003), Bupropion for the Treatment of Tobacco Dependence: Guidelines for Balancing Risks and Benefits, published in CNS Drugs , Wellbutrin is FDA-approved for both depression and smoking cessation aid, affirming its role in these therapeutic areas