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Case 1: What chronic insulin demand looks like on a glucose monitor One of our patients with established coronary heart disease wore a continuous glucose monitor (CGM) for a week before starting GLP-1 therapy (used off-label at the time to reduce cardiovascular risk)

Sitagliptin and vildagliptin are dipeptidyl peptidase-4 (DPP-4) inhibitors used in managing type 2 diabetes

If the side effects are too intense, the patient may need to continue taking the lower dosage for longer or may need to consider switching to a different medication or other weight loss alternatives

In conclusion, the present study revealed that overexpression of GLP-1R significantly reduces proliferation, migration and cytokine release in ASM cells from COPD patients

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