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Last reviewed: May 25, 2026 Last updated: May 25, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

"The FDA regulates brand-name GLP-1 drugs such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) and approves those drugs in very specific doses," says Katy Williams, MD, an MU Health Care family medicine doctor and bariatric medicine specialist

Duration of treatment and long-term outcomes This is where the philosophical divide between these two medication classes becomes most apparent

It is also important to keep GLP-1 pens away from the freezer compartment and not to store them in the door of the refrigerator, where temperature fluctuations are more common

Clinically, we are seeing that some patients report a reduced sense of reward from certain behaviors