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The image is characteristically that of a diffuse or mottled uptake in an enlarged gland, in striking contrast to the focal "cold" and "hot" areas of multinodular goiter

The human GI trial data (postoperative ileus studies) identified adverse events including nausea, dizziness, and injection site reactions

It also reduces inflammation

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4.1 Alkaloids 4.1.1 Berberine Berberine (BBR), extracted from the rhizomacoptidis, possesses multi-pharmacological effects, including antioxidative effects, reduction of mitochondrial injury, anti-inflammatory actions, autophagy regulation, and cell death (Hashemzaei and Rezaee, 2021