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And to put the risk in context, we're talking about roughly 7 people out of every 1,000 contracting hair loss within a year, compared to 5 people on SGLT-2 and 4 people on DPP-4, based on the figures

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For context, if an injectable 5 mg dose delivers 4 mg of active tirzepatide to the bloodstream (80 percent of 5 mg), a daily 5 mg ODT with 10 percent bioavailability would deliver 0.5 mg per day, or 3.5 mg per week

TB-500 is under FDA advisory review in July 2026, and FDA staff documents recommend caution because human safety and effectiveness data are limited

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