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Collectively, the failure of these clinical studies has raised doubts about the HDL hypothesis

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Sources: NHS website (Diabetic ketoacidosis, Hyperosmolar hyperglycaemic state, Hypoglycaemia, Underactive thyroid), MHRA Drug Safety Update (SGLT2 inhibitors and risk of DKA), NICE NG28 (Type 2 diabetes in adults) Frequently Asked Questions Can having hypothyroidism make my type 2 diabetes harder to control

Microdosing in this context means taking smaller-than-prescribed doses of semaglutide, often far below the clinically tested amounts