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Glucagon receptor activation increases basal metabolic rate, meaning the body actively burns more calories throughout the day

It is the next big bet for a global obesity market set to expand to $150 billion in value by next decade, where highly effective GLP-1 medications have already transformed treatment: making the class of drugs part of people's routines between a gym session and doing the daily Wordle

As a GIP/GLP-1 receptor agonist, tirzepatide enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying

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