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Previous research has shown that IFN- secreted by CD8 + T cells induces ferroptosis in tumor cells by regulating the expression of cystine/glutamate transporter (xCT), leading to lipid accumulation

Whilst in this this study the use of GLP-1RA was discontinued in 26.9% of cases due to adverse effects, the potential role of GLP-1RAs in improving metabolic control and reducing the risk of DKD progression in individuals with T1D can be considered

In sub-populations with pre-diabetes, Tao et al

The intestinal epithelial barrier has the function of preventing bacteria and other pathogens from entering the systemic circulation from intestinal tissues