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Mild-to-moderate kidney disease does not affect the dosage, but more severe kidney disease requires dosage reductions
Insurance companies typically restrict coverage to brand-name formulations like Ozempic or Mounjaro, which charge $900$1,400 monthly even with plan support
In both mice and rats, administration of ICV exendin-4(939) (Ex9), a potent GLP-1r antagonist, during oral glucose impairs glucose tolerance and reduces insulin levels (104, 209, 229)
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