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Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 25% of the global population [1] , and 20-30% of these cases progress to a more severe stage known as MASH [2]

Contact a healthcare provider if you have: Severe or persistent abdominal pain Pain that radiates to your back Vomiting that doesnt stop Signs of dehydration These could indicate more serious conditions (like pancreatitis, though rare)

Individuals with PWS have been found to have altered OFC responses to satiety in functional brain imaging studies (149)

This supports prioritizing GLP-1RA over insulin in patients requiring intensive glycemic control, potentially offering additional hepatoprotective benefits (Yang et al., 2024)

New Developments Drug companies are working on: Pills instead of shots Medicines that work even better Combinations with other drugs Lower-cost options As more options become available, youll have more choices for your care