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J., Kopec, J., Hyung, S
, 37 , 1421-1428, doi: Zhao, X., Lu, C., Chu, W., Zhang, Y., Zhang, B., Zeng, Q., Wang, R., Li, Z., Lv, B., and Liu, J
2396-C WESTERN DIET DAMPENS T REGULATORY CELL FUNCTION TO FUEL HEPATIC INFLAMMATION IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE Sudrishti Chaudhary 1 , Ravi Rai 1 , Pabitra Pal 1 , Dana Tedesco 2 , Aatur Singhi 3 , Satdarshan (Paul) Monga 1 , Arash Grakoui 2 , Smita Iyer 1 and Reben Raeman 1 , (1)University of Pittsburgh, (2)Emory University School of Medicine, (3)University of Pittsburgh Medical Center Background: The immunosuppressive T regulatory cells (Tregs) regulate immune responses and maintain immune homeostasis, yet their functions in metabolic dysfunction-associated steatotic liver disease (MASLD) pathogenesis remains controversial
doi: 10.1038/nrendo.2011.174 9 Rotondo DottoreGLeoMCasiniGLatrofaFCestariLSellari-FranceschiniSet al
The goal is not to eliminate exercise-induced oxidative stress entirely, which would potentially impair training adaptations, but to ensure that antioxidant defenses remain adequate to prevent excessive cellular damage while allowing beneficial adaptive signaling to occur
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