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According to historical records, the use of saffron in art dates back to approximately 1600-1700 BC, indicating its importance in early civilizations

These structural changes are primarily driven by chronic inflammation and oxidative stress, which induce apoptosis and fibrosis of alveolar walls

ERAD plays a protective role by clearing misfolded insulin and maintaining ER function, thereby supporting glucose-stimulated insulin secretion (GSIS)

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[7] [8] Side Effects and Toxicity There are no known side effects for MSM supplements in horses