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In MetS, events such as increased oxidative stress and inflammatory cytokines generated by hyperglycemia and obesity can cause vascular endothelial dysfunction, compromising the vasomotor balance and increasing the adhesion of leukocytes to the endothelium in various organs and tissues, including the central nervous system (CNS) [7,8,9]

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It may have been after a long night out or a hard day at work, but the next day she's probably regretted it as the sheets and her skin looked rough