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Controlled storage conditions minimise such degradation pathways

Age and degree of GH axis decline: Patients in their late 40s and 50s typically see more dramatic early results than patients in their mid-30s starting preventively, because GH decline is more advanced and the pituitary still has enough reserve capacity to respond meaningfully to stimulation

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Sim R, Bogdanov P, Ramos H, et al

We also discuss how animals and people establish themselves in a group hierarchy by rank and how the brain responds to dominance and subordination