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PubMed Central,

This dehydration can also increase the risk of kidney injury, especially in those with pre-existing kidney conditions

[35] Medical uses [edit] European Union [edit] In the European Union, semaglutide is indicated for the treatment of adults with insufficiently controlled type 2 diabetes as an adjunct to diet and exercise as monotherapy when metformin is considered inappropriate due to intolerance or contraindications, [16] [17] in addition to other medicinal products for the treatment of diabetes