Collaboration between providers and patients remains essential for success
It happens with bariatric surgery, extreme caloric restriction, and other pharmacological weight loss interventions
Third, although the notion of enhancing healthspan and potentially prolonging lifespan through GLP-1 RA treatment is appealing, its application to asymptomatic individuals in clinical settings is still primarily theoretical and lacks robust empirical support at this time
Instead of acting on the central nervous system, they target metabolic pathways that regulate appetite, insulin secretion, and digestion
Several alternative therapeutic strategies have been investigated, including protein kinase C inhibitors [10], darbepoetin alfa [11], endothelin receptor antagonists (ERAs) [12], direct renin inhibitors [13], nuclear factor erythroid 2-related factor 2 activators [14], and combination of ACE inhibitor and ARB [15]