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Clinical differences between medications Mounjaro and Saxenda differ in three key ways: Injection frequency: Mounjaro requires one injection weekly, while Saxenda needs daily injections Hormone targets: Mounjaro affects both GLP-1 and GIP hormones, while Saxenda only targets GLP-1 Duration of action: Mounjaro maintains more consistent levels in your body over time compared to Saxendas daily fluctuations These differences explain why the transition process requires starting at Mounjaros lowest dose your body needs time to adjust to this new dual-action effect

In the efficacy-estimand analysis, participants taking the highest dose (12 mg) lost an average of 28.7% of their body weight at 68 weeks, about 71.2 pounds from a baseline of 248.5 pounds