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adults are overweight or obese, only four percent of these people are prescribed GLP-1 weight-loss medicines due to concerns about safety or effectiveness, lack of healthcare provider training in weight management, excessive costs due to insurance companies refusing coverage and a toxic stigma that portrays obesity as a lack of willpower

This is due to the generation of super oxides, inactivation of oxidoreductase, and oxidation of glutathione, leading to a 45% decrease in overall tissue content [50]

These drugs are primarily used to manage type 2 diabetes by helping to control blood sugar levels

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Researchers believe GIP co-activation may have a protective effect on the GI tract, explaining why dual and triple agonists are often better tolerated than single-agonist Semaglutide (which has 44% nausea rates)