GLP-1 medications are eliminated through renal pathways, and reduced kidney function affects both drug tolerance and the risk of complications particularly dehydration-related acute kidney injury, which can occur when GI side effects (nausea, vomiting) reduce fluid intake
Understanding this broadens the perspective
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EASY SOURCE OF ANTIOXIDANTS - Reduced L- glutathione is found in Spinach, avocados, asparagus and okra
5.1.2 Enhancement of gut and bloodbrain barrier integrity Recent studies have shown that a vicious cycle of inflammation and oxidative stress is created at the renal level by the influx of uremic toxins and urea into the gastrointestinal lumen via the enterohepatic cycle, which exerts a selective pressure that encourages the excessive growth of bacterial species that produce urease, uricase, indole, and p-cresol-forming enzymes with a reduction in SCFAs-producing species (Vaziri et al., 2013
