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The modification is intended to protect the molecule from premature oxidation or breakdown

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Description Overview IGF-1 LR3 is a recombinant analog of human IGF-1 with two key modifications: an arginine substitution at position 3 (R3) and a 13amino acid N-terminal extension (Long, derived from methionyl porcine GH)

As seen with blood cells, a fast high-capacity binding, which was diminished by phloretin, was recorded, suggesting that this metabolite is actively distributed into endothelial cells as well