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It is important to develop a single pharmacological medication with multiple functions, such as tirzepatide

Owing to its -helical binding conformation, GLP-1 stroke us as both a good model for testing -helix mimicry with oligourea foldamers and a relevant pharmaceutical target

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Clinical trial data shows that up to 50% of participants experienced some form of abdominal distension during treatment, with symptoms most pronounced during dose escalation and the early weeks