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Patients frequently describe a profound, crushing fatigue that does not improve with rest, accompanied by a thick, disorienting cognitive impairment commonly referred to as "brain fog." For those living with these invisible illnesses, the frustration of navigating a medical system that often lacks clear answers can be just as exhausting as the physical symptoms themselves

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Furthermore, glutathionylated residue C151 of roGFP2 reacted three to four times faster than glutathionylated residue C208, which is again the opposed reactivity as observed for the oxidation kinetics of both monothiol roGFP2 variants (Table 1)