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Clinical Evidence in Asian Indian Patients The Indian thin fat phenotype is more prone to the development of T2DM and is associated with several unique features, such as early age of T2DM onset, early decline in beta cell mass, higher insulin resistance, higher carbohydrate intake and physical inactivity leading to central obesity, unique dyslipidemia pattern, increased CV disease risk, higher association with nonalcoholic fatty liver disease, among others [29,30,31]

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The specific structure of GLP-1 was identified in 1983

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