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This impairment of DNA synthesis affects the rapidly dividing cells of the bone marrow earlier than other cells, resulting in the production of large, immature, hemoglobin-poor red blood cells (macrocytosis), as well as effects on white blood cells, including abnormal (hypersegmented) neutrophils and reduced overall cell counts (pancytopenia)

doi: 10.3389/fphys.2014.00036

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Researchers assess its effects on neuronal survival, glial scarring, and the modulation of neurotransmitter systems, such as the dopaminergic and serotonergic systems