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Finally, the absence of gut microbiome and hepatic metabolism data limits mechanistic interpretation, particularly for diet-responsive metabolites such as coumarin

To further elucidate the contribution of Erbin-deficient platelets/MKs during antitumor immunity, they employed adoptive cell transfer therapy (ACT) by transferring MKs or platelets isolated from Erbin cKO mice to WT mice, respectively

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In particular, the first study demonstrated that, along with improvements in anthropometric parameters, HOMA-IR reduced in both treatment arms, but liraglutide 1.2 mg/day was superior to metformin also in reducing glucose levels at 120 min during OGTT [57]

Dynamic regulation of mitochondrial function by glucocorticoids