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Liver Issues Those who suffer from liver disorders are often unable to store B12

However, we cannot discount that other uncharacterized stress response pathways may be contributing to our observed phenotypes by sensing and responding to levels of undecaprenyl phosphate or peptidoglycan matrix defects

It is the most abundant endogenous antioxidant in the human body, central to Phase II detoxification in the liver, reactive oxygen species (ROS) neutralisation, immune signalling, and maintenance of cellular redox homeostasis

doi: 10.3109/15563650.2014.946994 [PubMed] 25767408 Mahmoudi GA, Astaraki P, Mohtashami AZ, Ahadi M