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The Dox breeding trial (Fig

Finally, we identified that inactivation of p53 was the key mechanism involved in restoring the expression of system xCT, thus suggesting the beneficial effects of LA on anti-ferroptosis in FA-induced AKI

In laboratory investigations, MT-1 functions as a melanocortin receptor agonist, binding to and activating members of the melanocortin receptor family (MC1R, MC3R, MC4R, MC5R)