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High-protein diets can increase renal metabolic burden and promote the generation of harmful metabolites derived from intestinal protein fermentation, while Western dietary patterns characterized by high fat and sugar intake are closely associated with insulin resistance, chronic low-grade inflammation, and gut microbiota dysbiosis ( The human intestinal tract is colonized by trillions of microorganisms that participate in various physiological processes including food digestion, synthesis of essential vitamins and amino acids, pathogen antagonism, and toxin clearance ( A close triangular interaction exists among diet, gut microbiota, and host metabolism

A Background on Saffron The story of Supresa begins with Crocus sativus L ., commonly known as saffron crocus

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Global NASH Council, American Association for the Study of Liver Diseases (AASLD), EASL | The Home of Hepatology, Canadian Association for the Study of the Liver, European Liver Patients' Association - ELPA, Global Liver Institute, Priti Chawla, Obesity Matters, American Diabetes Association Fatty Liver Alliances Post GLP-1 receptor agonists (GLP-1RAs) show promise in managing metabolic dysfunction-associated steatotic liver disease (MASLD) by reducing hepatic steatosis, resolving MASH, and mitigating fibrosis progression

1 Lilly posted $65.18 billion in FY2025 revenue, up 44.7% year-over-year, the largest growth rate among the top 20 pharma companies