Sources: Neelakantan et al., Biochem Pharmacol 2018 | Dimet-Wiley et al., Sci Rep 2024 Security Profile & Chemical Identity Molecular specifications and preclinical safety data 5-Amino-1MQ Chemical Identity A small molecule derived from quinolinium salts, developed at the University of Texas (2017) 5-Amino-1MQ Tolerance & Status Safety data from preclinical studies (DIO mouse model) Published Preclinical Data 3 key studies published in Biochemical Pharmacology and Scientific Reports 35% Reduction of white adipose tissue in 11 days (20 mg/kg, 3 times/day) Physical Effects (11 days) + 40 % Improvement of grip strength in aged mice (22-24 months) Strength & Performance (aged mice) microbiome The combination of 5-Amino-1MQ + caloric restriction establishes a distinct gut microbial profile Protocol & Results Important Notice Search Only Not intended for human consumption
The UK regimen is typically 1 mg three times weekly for 2 weeks, then 1 mg every 23 months for maintenance
Generally, after 812 weeks of continuous use, a 4-week washout period is required to avoid tolerance from long-term continuous use
Gastroenterology 139 (4), 11151127
It is thought that when lambs are injected with Vitamin B12, there can be an up to 25% increase in live weight gain for a short period (up to 10 days) due to the positive effect on the metabolism