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By exponentially increasing the production of Glutathione S-transferases (GSTs) and supplying necessary sulfur for the sulfation pathway, NAC ensures that the liver can safely conjugate and excrete toxic intermediate metabolites without causing secondary tissue damage

These changes were correlated with altered activities of reactive oxygen species (ROS) and lipid biosynthesis-related enzymes, highlighting the pivotal role of MT in lipid accumulation (Li et al., 2017)

Reference per Shay 2009 mechanistic review: American Diabetes Association Professional Practice Committee

Recommended Use: Take 1 ml (approximately 2 pumps) and hold in the mouth for 30 seconds before swallowing, or as directed by your healthcare practitioner

Further, cysteine dioxygenase is downregulated, which appears to account for the increment in the cysteine availability for GSH synthesis in the rats supplemented with betaine [57]