2 mg semaglutide to tirzepatide Early Dose Escalation of after Switching from in Type Diabetes Mellitus Semaglutide Dose Escalation vs Tirzepatide

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GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the GIP/GLP-1 dual agonist tirzepatide were studied in STEP (semaglutide, NEJM 2021), SURMOUNT (tirzepatide, NEJM 2022), and SURMOUNT-OSA (tirzepatide for obstructive sleep apnea, NEJM 2024)

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3.3 Sensitivity analysis The results of the DSA are presented in Figure 2 in the form of a tornado graph illustrating the 11 most influential parameters impacting the base-case ICER

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