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Liuwei Dihuang Pill, integrating Rehmannia, Coptis, and Cornu Cervi Pantotrichum, inhibits TGF-1/MAPK signaling to reduce inflammation and interstitial fibrosis (Zhu et al., 2024)

As for the patient base, a recent report found that 75% of patients stop taking the medications within two years, although the report did not elaborate on the causes of this decline in use, which may be partially attributable to factors such as high costs and self-funding requirements