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This is a potentially lethal complication of metformin therapy that typically occurs when renal dysfunction results in very high blood metformin levels, which inhibit mitochondrial function resulting in the overproduction of lactate (53)

Patients with Duchenne dystrophy and Becker dystrophy showed lower carnitine levels in muscle biopsies than controls [131] though these levels were higher than in patients suffering primary carnitine deficiency as a result of severe muscle damage [1]

Its chemical stability and non-toxic copper delivery capacity further underscore its utility as a molecular tool for investigating gene expression, tissue regeneration, and copper-mediated biochemical processes (Pickart, Vasquez-Soltero, and Margolina 2012)

Hemichannels are required for amyloid beta-peptide-induced degranulation and are activated in brain mast cells of APPswe/PS1dE9 mice

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