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Health ABC Study
Nimesulide (219), Vismodegib (220), New Pyrimidine-5-Carbonitriles (221), Sulfonamide-Pyrazole derivatives (222) and lariciresinol (223) exert regulatory effects on arachidonic acid metabolism by inhibiting COX-2, the specific drugs used are shown in Table 5
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In addition, we observed that HIF-1 protein levels accumulate downstream of mTOR in response to GLP-1R signalling, whereas we also demonstrated that depletion of HIF-1 impaired effects on glycolysis and transcriptional regulation of glycolytic genes
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